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When it comes back, it’s likely to hit hardest areas not severely infected the first time, said Gregory Poland, a professor of medicine at the Mayo Clinic in Rochester, Minnesota, and editor-in-chief of the journal Vaccine.

“This outbreak has predominantly been on the two coasts. Wave 2 will be in the interior of the county where there are a lot of susceptible people,” he said.
...
COVID-19’s sweet spot could be the same as influenza, roughly October to May, with a peak between October and November, modeling suggests. If it does behave like influenza, it will move to the Southern hemisphere for winter there, then return to the Northern hemisphere for its cold months.

“To anthropomorphize, the virus will come back here looking for new victims,” Poland said.
...
There’s a cautionary tale from the 2003 outbreak of SARS in Toronto, which infected 375 people there and killed 44. The city took expanded precautions beginning in March, but they were lifted in May when it appeared the outbreak was over. It wasn’t.

“Toronto took the brakes off," Hanage said. "They had a flare, and it took them weeks to get it back under control.”